Diabetes Genome Anatomy Project

Resources > Microarray Data

Microarray Data

The following are Affymetrix GeneChip® Microarray Data generated by the various DGAP Projects. The data are housed in the ChipperDB database. Please follow the links below to obtain detailed information on each study, or to download raw data files for use in microarray analysis tools.

Cellular Studies

• Effect of PGC-1alpha and PGC-1beta on gene expression in myocytes and hepatocytes [ B. Spiegelman Lab, DFCI ]
  Download: All CEL Files | All TXT Files
• 3T3-L1 Adipocyte Differentiation - Time Course [ M. Czech Lab, UMASS ]
  Download: All CEL Files | All TXT Files
• 3T3-L1 Fibroblast Cells, 3T3-L1 Adipocyte Cells, and Mouse Skeletal [ M. Czech Lab, UMASS ]
  Download: All CEL Files | All TXT Files
• Brown preadipocyte IRS knockout profiling [ C.R. Kahn Lab, Joslin ]
  Download: All CEL Files | All TXT Files

In Vivo studies - Rodent

• Transcription profiling of wild type and PGC-1alpha KO liver and skeletal muscle [ B. Spiegelman Lab, DFCI ]
  Download: All CEL Files | All TXT Files
• 3T3-L1 Fibroblast Cells, 3T3-L1 Adipocyte Cells, and Mouse Skeletal [ M. Czech Lab, UMASS ]
  Download: All CEL Files | All TXT Files
• Liver - ob/ob mice [ C.R. Kahn Lab, Joslin ]
  Download: All CEL Files | All TXT Files
• Mouse skeletal muscle - controls, streptozotocin diabetes and insulin treated [ C.R. Kahn Lab, Joslin ]
  Download: All CEL Files | All TXT Files
• Isolated adipocytes from normal and fat insulin receptor knockout (FIRKO) mice sorted into small and large cells [ C.R. Kahn Lab, Joslin ]
  Download: All CEL Files | All TXT Files
• Skeletal Muscle - Muscle Insulin Receptor Knockout and Control Mice - Control, Streptozotocin Diabetic and Insulin Treated [ C.R. Kahn Lab, Joslin ]
  Download: Excel Spreadsheet of Mean expression measures | All CEL Files | All TXT Files
• Effect of insulin infusion on skeletal muscle [ C.R. Kahn Lab, Joslin ]
  Download: All CEL Files | All TXT Files
• Comparison of Low Fat and High Fat Diet on Mice of Two Genetic Backgrounds (B6 vs. 129) - Fat
  Download: All CEL Files | All TXT Files
• Comparison of Low Fat and High Fat Diet on Mice of Two Genetic Backgrounds (B6 vs. 129) - Liver
  Download: All CEL Files | All TXT Files
• Comparison of Low Fat and High Fat Diet on Mice of Two Genetic Backgrounds (B6 vs. 129) - Skeletal Muscle
  Download: All CEL Files | All TXT Files
• Control Insulin Receptor (IR) and IRS-1 Single and Double Heterozygous (DH) Knockouts - Comparison of Age (6 weeks vs 6 months) and Genetic Background (B6 vs. 129) - Epididymal White Fat
  Download: All CEL Files | All TXT Files
• Control Insulin Receptor (IR) and IRS-1 Single and Double Heterozygous (DH) Knockouts - Comparison of Age (6 weeks vs 6 months) and Genetic Background (B6 vs. 129) - Liver
  Download: All CEL Files | All TXT Files
• Control Insulin Receptor (IR) and IRS-1 Single and Double Heterozygous (DH) Knockouts - Comparison of Age (6 weeks vs 6 months) and Genetic Background (B6 vs. 129) - Skeletal Muscle
  Download: All CEL Files | All TXT Files

In Vivo Studies - Human

• Human skeletal muscle - type 2 diabetes - Swedish males [ D. Altshuler Lab, M.I.T. ]
  Download: All CEL Files | All TXT Files
• Human skeletal muscle - type 2 diabetes and family history positive individuals - Mexican American [ M.E. Patti Lab, Joslin ]
  Download: All CEL Files | All TXT Files
• Human pancreatic islets from normal and Type 2 diabetic subjects [ C.R. Kahn Lab, Joslin ]
  Download: All CEL Files | All TXT Files